Drew Kaser Jerseys Stitched , 1 p.m. ET, CBSOPENING LINE — Chargers by 7 1/2RECORD VS. SPREAD — Los Angeles 0-1, Buffalo 0-1SERIES RECORD — Chargers lead 24-12-2LAST MEETING — Chargers beat Bills 54-24, Nov. 19, 2017LAST WEEK — Chargers lost to Chiefs 38-28; Bills lost to Ravens 47-3AP PRO32 RANKING — Chargers No. 19, Bills No. 32CHARGERS OFFENSE — OVERALL (1), RUSH (11), PASS (2).CHARGERS DEFENSE — OVERALL (20) Easton Stick Los Angeles Chargers Jerseys , RUSH (13), PASS (22).BILLS OFFENSE — OVERALL (32), RUSH (25), PASS (32).BILLS DEFENSE — OVERALL (22), RUSH (19), PASS (21).STREAKS, STATS AND NOTES — Chargers coach Anthony Lynn served as Bills interim coach for 2016 season finale after Rex Ryan was fired. Lynn was candidate for Bills job before Sean McDermott got it. … Chargers have won three straight and 17 of past 22 meetings. … Chargers have outscored Bills by combined 113-44 in past three meetings, and not trailed since 23-14 loss on Oct. 19 Los Angeles Chargers Jerseys 2019 , 2008. … QB Philip Rivers is 4-1 against Bills with 1,115 yards passing, 10 touchdowns and one interception. With 424 yards passing against Chiefs, Rivers topped 400 yards for 10th time — tied for fourth on NFL career list. … RB Melvin Gordon had career-best 102 yards receiving against Chiefs. … CB Casey Hayward intercepted two of Bills QB Nathan Peterman’s five first-half interceptions in last meeting. … Bills first-round pick QB Josh Allen to make first career start after Peterman went 5 of 18 for 24 yards and two interceptions in two-plus quarters against Ravens. … Bills traded up five spots to select Allen out of Wyoming — highest in draft order Buffalo has chosen QB. Allen finished 6 of 15 for 74 yards and 26 yards rushing last week. … Bills only NFL team to not score TD in Week 1. … RB LeSean McCoy had 22 yards rushing on seven carries, and one catch for minus-1 yard. … Loss to Ravens was Bills’ second-most lopsided margin of defeat, behind 56-10 loss to New England on Nov. 18, 2007. … Buffalo managed 153 yards offense against Ravens, fewest since 145 in 40-7 loss at Chicago on Oct. 8 Youth Easton Stick Jersey , 2006. … Defense allowed Ravens to score six touchdowns on six trips inside 20. … First-round pick LB Tremaine Edmunds became Bills’ first rookie to have sack in season opener since 2002. … Fantasy Tip: Pick your poison with Rivers and Gordon both having chances of putting up big numbers. Chargers’ defense worth consideration against Bills popgun attack and patchwork offensive line. Melvin Gordon has a sprained MCL, which is expected to sideline him for a few weeks. Chargers coach Anthony Lynn, though, isn’t even ready to rule out the running back for Sunday.鈥淚t鈥檚 highly doubtful that he鈥檒l play this week but never count that guy out,” Lynn said Monday, via Ryan Kartje of the .Gordon was injured on a trick play in the third quarter on a tackle by Cardinals defensive lineman Robert Nkemdiche in the backfield. The Chargers feared the worst, so Lynn called the diagnosis “good news” and said he was “very relieved.”The Chargers “absolutely” expect Gordon to return before the end of the regular season.鈥淚鈥檝e had MCL鈥檚, and I know you can recover quickly from those Easton Stick Jersey Color Rush ,鈥?Lynn said. 鈥淢elvin is a fast healer. I was relieved. When you saw it on the field, it looked pretty nasty because it was a leg whip. I thought he came out on the good end of this one.鈥?The Chargers will fill in with Austin Ekeler and Justin Jackson. They also have Detrez Newsome. But they will miss Gordon, who has 802 yards and nine touchdowns on 153 attempts this season. He has missed only one game this season, sitting out the Tennessee game with a hamstring issue.